Tittle: Bio-conjugation Scientist
Location: South San Francisco, CA 100 % Onsite
Duration: 12 Months Contract Position
Education Requirement:
• Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.
Experience and Skills Required:
• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.
Nice to have skills:
• Biologics analytic experience, purification techniques.
• Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.
• Personality: Team player, Adheres to timeline, Communicative and collaborative.
Responsibilities:
• The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent Client medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
• Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
• Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.
Specific responsibilities will include:
• Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
• Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
• Acquisition and interpretation of analytical data such as LC/MS.
